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. 2020 Sep 2;10:14491. doi: 10.1038/s41598-020-71559-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Prognostic value associated with GLI(1/2), HH(S/I/D) and TGFB(1/2/3) genes and the mesenchymal/EMT, cell stemness and cell cycle metagenes in human cancers. (A) Data were derived from a meta-analysis for the univariate prognostic value for overall survival in 26 types of human cancers for which sufficient events were available. Bigger circles represent lower p values. Marked colors represent p value below 0.001, dull colors represent p values below 0.05. Green and red colors represent H.R. below and above 1, respectively (see scale bar). (B) Correlations between pan-cancer profiles of prognostic scores of GLI(1/2), HH(S/I/D) and TGFB(1/2/3) genes and the mesenchymal/EMT, cell stemness and cell cycle metagenes. Prognostic scores are defined as the log2(H.R.) if the related p-value is below 0.05, or 0 otherwise.