Table 3.
Analysis of synaptic protein expression.
Synaptic protein | Expression in NL3R451C mice compared to WT | ||
---|---|---|---|
Cortex | Striatum | Cerebellum | |
PSD-95 |
81 ± 3.2% p = 0.071 |
129 ± 8.6% p = 0.01* |
101 ± 7.6% p = 0.95 |
PSD-93 |
93 ± 9.5% p = 0.58 |
83 ± 9.7% p = 0.28 |
106 ± 8.8% p = 0.66 |
NL2 |
90 ± 10% p = 0.52 |
102 ± 5.7% p = 0.80 |
117 ± 18% p = 0.45 |
SYT-1 |
103 ± 6.8% p = 0.79 |
77 ± 6.9% p = 0.092 |
160 ± 23% p = 0.12 |
SNAP-25 |
67 ± 4.8% p = 0.003** |
85 ± 6.8% p = 0.28 |
105 ± 13% p = 0.78 |
GFAP |
72 ± 12% p = 0.27 |
96 ± 11% p = 0.84 |
74 ± 14% p = 0.32 |
The bold, italics font highlights statistically significant differences between genotypes: *p < 0.05, **p < 0.01.