Title {1}	Efficacy and safety of Jia Wei Bushen Yiqi formulas as an adjunct therapy to systemic glucocorticoids on acute exacerbation of COPD: Study protocol for a randomized, double-blinded, multi-centre, placebo-controlled clinical trial TCMWSG: Traditional Chinese Medicine with Systemic Glucocorticoids
Trial registration {2a and 2b}.	ID: ChiCTR1900023364, registered on 24 May 2019. www.chictr.org.cn
Protocol version {3}	KY 2019-299,03,03, July, 2019
Funding {4}	This project was supported for 3 years to accelerate the development of Chinese medicine in Shanghai, China. [Grant No: ZY (2018-2020)-FWTX-4016], the National Natural Science Foundation of China (Grant No. 81704154), Chinese medicine innovation project of Shanghai Health Committee (No.ZYKC201601023) and National Natural Science Foundation of China (No.81501180)
Author details {5a}	Qing Kong1#, Shuming Mo2#, Wenqian Wang1, Zihui Tang1, Ying Wei1, Yijie Du1, Baojun Liu1, Lingwen Kong1, Yubao Lv1* Jingcheng Dong1* 1Department of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, China, 2Department of Integrative Medicine, North Hospital of Huashan Hospital, Fudan University, Shanghai, China *Correspondence: Yubao Lv, lvyubao80313@163.com *Correspondence: Jingcheng Dong, jingcheng_dong@yeah.net #These authors have contributed equally to this project.
Name and contact information for the trial sponsor {5b}	Jingcheng Dong, jingcheng_dong@yeah.net
Role of sponsor {5c}	Qing Kong and Shuming Mo drafted the manuscript. Wenqian Wang, Zihui Tang, Baojun Liu, Yijie Du and Lingwen Kong participated in the design of the study. Ying Wei, Yubao Lv and Jingcheng Dong conceived the study, participated in its design and coordination, and drafted the manuscript. All authors read and approved the final manuscript.