Figure 3.

Median change in percent of tumor core volume between baseline and follow-up over all tumors in all subjects that was above (${\mathit{AUC}}_{90s}$, $v_p$_, and $k^{\mathit{trans}}$) or below (ADC, ADC (S/I), T1, and $v_e$) a rolling value for each parameter. The values that yielded the greatest absolute differences (Thres_opt, dashed green line) were used as thresholds to calculate the “target sub-population of tumor voxels” ($\mathrm{\Delta }Vol$) per parameter in each analyzed tumor.