Table 1.

Characteristics of starting material and release specifications of generated products.

Donor	EBV	CMV	Line	Streptamer		Starting material			Directly after isolation			End of culture
	status	status
	donor	donor
				1	2	MNC	Strept	Strept	Cells	Strept	Strept	Cells	CD3	Strept	Strept	HA1-	Total
							1	2		1	2			1	2	TCR	tetramer
						(106)	(%)	(%)	(106)	(%)	(%)	(106)	(%)	(%)	(%)	(%)	pos (%)
001	pos	pos	1	CMV-pp50-A1-VTE	EBV-BZLF1-B8-RAK	1590	1.2	1.2	10.5	49	45	283	99	27	33	39	94
			2	CMV-pp50-A1-VTE	EBV-BZLF1-B8-RAK	1890	1.2	1.8	8.3	52	45	228	98	27	26	36	97
002	pos	neg	1	EBV-BMLF1-A2-GLC	–	2351	0.2	–	1.7	72	–	3.1	99	59	–	41	100
			2	EBV-BMLF1-A2-GLC	–	2341	0.2	–	0.6	n.d.	–	2.9	97	44	–	30	83
003	pos	neg	1	EBV-BMLF1-A2-GLC	EBV-BZLF1-B8-RAK	2272	0.05	0.53	7.6	2.6	49	101	97	13	30	30	74
			2	EBV-BMLF1-A2-GLC	EBV-BZLF1-B8-RAK	2024	0.04	0.55	3.8	2.8	52	15	97	15	32	18	78
004	pos	neg	1*
005	pos	pos	1	CMV-pp65-A2-NLV	EBV-EBNA3A-B7-RPP	1480	0.04	0.07	0.8	17	36	88	99	4.5	56	35	97
			2	CMV-pp65-A2-NLV	EBV-EBNA3A-B7-RPP	985	0.03	0.05	0.22	n.d.	n.d.	54	96	3.6	58	33	98
006	pos	neg	1*
007	pos	neg	1	EBV-EBNA3A-B7-RPP	EBV-BZLF1-B8-RAK	1826	0.1	1.5	10.4	8	84	44	99	58	9.3	11	97
			2*	EBV-EBNA3A-B7-RPP	EBV-BZLF1-B8-RAK	2000	0.1	1.4	4.6	10	87	21.6	99	64	15	13	99
008	pos	neg	1*
009	pos	neg	1*	EBV-BMLF1-A2-GLC	–	2074	0.1	–	0.7	80	–	0.16	84	72	–	5	77

^*No infusion of HA1H TCR-transduced T cells.