Figure 7.

Comparison of immune cell subsets and ratios between placental lesions within the FGR cohort. (A) Numbers of cells/mm² are shown for CD68⁺ macrophages, CD206⁺ M2 macrophages, CD3⁺ T cells, FOXP3⁺ Treg cells, and CD56⁺ NK cells and compared between placental lesions [MVM (n = 18), FVM (n = 17), CA (n = 27), VUE (n = 45), ML (n = 44), and NL (n = 44)] within the FGR cohort with the Kruskal Wallis test and pairwise Dunn's non-parametric comparison test as post-hoc test. Data presented as median + IQR. *p < 0.05, **p < 0.01, ***p < 0.001. (B) Ratios of number of cells/mm² are shown for CD206⁺/CD68⁺ macrophages and FOXP3⁺/CD3⁺ T cells and compared between placental lesions within the FGR cohort with the Kruskal Wallis test and pairwise Dunn's non-parametric comparison test as post-hoc test. Data presented as median + IQR. *p < 0.05, **p < 0.01. MVM, maternal vascular malperfusion; FVM, fetal vascular malperfusion; CA, chorioamnionitis; VUE, villitis of unknown etiology; ML, multiple lesions; NL, no lesions.