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. 2020 Aug 20;11:1898. doi: 10.3389/fimmu.2020.01898

Table 1.

Patient characteristics of the FGR, SB, and control cohort.

Control (n = 42) FGR (n = 250) SB (n = 64)
Maternal age (years) 31.51 ± 4.83 29.39 ± 5.50 31.66 ± 4.84
Maternal BMI (kg/m2) 23.66 ± 5.30 27.12 ± 5.50
Smoking during pregnancy 10 (23.8%) 100 (40%)* 18 (28.1%)
Parity
   Nulli (0) 19 (45.2%) 152 (60.8%) 29 (43.8%)
   Primi (1) 15 (35.7%) 60 (24%) 13 (20.3%)
   Multi (24) 5 (19.0%) 35 (14%) 19 (28.1%)
   Grande multi (>4) 0 (0%) 3 (1.2%) 3 (4.7%)
GA at birth (days) 278.45 ± 11.98 270.45 ± 9.83*** 275.33 ± 11.32***
Sex
   Boy 23 (54.8%) 101 (40.4%) 32 (50%)
   Girl 19 (45.2%) 147 (58.8%) 30 (46.9%)
Neonatal weight (grams) 3464.88 ±457.48 2296.42 ± 340.52*** 3169.52 ± 639.821***
Neonatal weight centile
    <p3 0 (0%) 203 (81.2%)*** 12 (18.8%)***
   p3–p5 0 (0%) 16 (6.4%) 6 (9.4%)
   p5–p10 0 (0%) 15 (6.0%) 4 (6.3%)
   >p10 42 (100%) 14 (5.6%) 40 (62.6%)
Placental weight (grams) 537.00 ± 97.14 360.71 ± 86,46*** 436.18 ± 113.49***

Patient characteristics are shown for the FGR (n = 250), SB (n = 64), and control (n = 42) cohorts. Continuous data is presented as mean + SD and compared between groups using the one-way ANOVA with Tukey HSD as a post-hoc test. Categorical data is presented as number + percentage and compared using the Chi-square test with Bonferroni correction as a post-hoc test. Significance presented as p-value compared to the control group.

*

Significant at p < 0.05.

***

Significant at p < 0.001. FGR, fetal growth restriction; SB, stillbirth; GA, gestational age.