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Effects of UII and urantide on VCAM-1 and ICAM-1 expression in HUVECs (a–e). Dose dependent mRNA levels of VCAM-1 and ICAM-1 (a, b); protein expression levels of VCAM-1 and ICAM-1 after treatment with 50 nM UII with or without urantide (n = 3 for each group) (c, d, e); and plasma UII levels in CAD patients (n = 24 for males and n = 16 for females) (f). Data are expressed as the mean ± SEM. *P < 0.05 and **P < 0.01
