Figure 1.
The histopathological features of IV injection of LPS E. coli O55 B5 with or without meloxicam and dexamethasone treatment on lung injury (H&E, ×100). (A) Negative control: four hours after IV injection of pyrogen-free water, arrow: interatrial septum; (B) Positive control: four hours after IV injection of LPS E. coli O55 B5; (C) LPS+ meloxicam 0.5: four hours after IV injection of LPS E. coli O55 B5 and IM injection of 0.5 mg/kg meloxicam; (D) LPS+ meloxicam 2: four hours after IV injection of LPS E. coli O55 B5 and IM injection of 2 mg/kg meloxicam; (E) LPS+ dexamethasone 2: four hours after IV injection of LPS E. coli O55 B5 and IM injection of 2 mg/kg meloxicam; (F) LPS+ dexamethasone 4: four hours after IV injection of LPS E. coli O55 B5 and IM injection of 4 mg/kg meloxicam.
Abbreviations:E. coli, Escherichia coli; H&E, hematoxylin and eosin; IM, intramuscular; IV, intravenous; LPS, lipopolysaccharide.