Table 1.
DEMOGRAPHICS | |
---|---|
Total, No. (%) | 105 (100) |
Female, No. (%) | 65 (61.9) |
Age at onset, median (IQR), y | 31 (25–46) |
CLINICAL FEATURES | |
Phenotype, No. (%) | |
Optic neuritis | 11 (10.5) |
Myelopathy | 51 (48.6) |
Brainstem/Cerebellar syndrome | 24 (22.9) |
Hemispheric syndrome | 4 (3.8) |
Polyfocal | 15 (14.3) |
Fulfillment of DIS at baseline | 42 (40%) |
Patients with cranial MRI at baseline | 105 (100) |
Cranial MRI load (IQR) | 3.5 (2–4) |
Patients with spinal MRI at baseline | 95 (90.5) |
Spinal MRI load (IQR) | 1 (0–2) |
EDSS score at baseline (IQR) | 2 (2–3) |
PARACLINICAL FEATURES | |
CSF cell count (IQR) | 9 (7–14) |
CSF protein (IQR), mg/dl | 35 (21–48) |
OCB positivity, No. (%) | 61 (58.1) |
IgG index | 0.64 (0.50–0.81) |
IgG index elevation, No. (%) | 44 (41.9) |
FOLLOW-UP | |
CDMS at follow-up, No. (%) | 69 (65.7) |
McDonlad MS at follow-up, No. (%) | 80 (76.2) |
Time to CDMS (IQR), m | 12 (5.5–27.5) |
Follow-up duration (IQR), m | 32 (23–67) |
CDMS, clinically definite multiple sclerosis; CSF, cerebrospinal fluid; DIS, dissemination in space; EDSS, Expanded Disability Status Scale; IgG, immunoglobulin G; IQR, interquartile range; MRI, magnetic resonance imaging; OCB, oligoclonal band.