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. 2020 Aug 20;11:1994. doi: 10.3389/fimmu.2020.01994

TABLE 2.

Significantly discriminative taxa between the twenty-eight Encephalitis patients and healthy subjects determined by Mann-Whitney U tests.

Taxa Encephalitis, M (IQR) Control, M (IQR) p value
The taxa increased in encephalitis patients
Phylum Proteobacteria 0.138 (0.084–0.241) 0.068 (0.052–0.116) 0.001
Class Bacilli 0.015 (0.006–0.028) 0.004 (0.002–0.007) <0.001
Class Gammaproteobacteria 0.096 (0.046–0.195) 0.026 (0.016–0.074) <0.001
Order Lactobacillales 0.014 (0.006–0.027) 0.003 (0.002–0.007) <0.001
Order Erysipelotrichales 0.008 (0.004–0.034) 0.004 (0.003–0.006) 0.011
Order Enterobacteriales 0.081 (0.041–0.191) 0.024 (0.013–0.058) <0.001
Family Porphyromonadaceae 0.042 (0.026–0.110) 0.016 (0.010–0.022) <0.001
Family Enterobacteriaceae 0.081 (0.041–0.191) 0.024 (0.013–0.058) <0.001
Genus Parabacteroides 0.041 (0.026–0.110) 0.016 (0.010–0.021) <0.001
Family Rikenellaceae, genus undefined 0.024 (0.009–0.043) 0.010 (0.004–0.017) 0.001
Family S24-7, genus undefined 0.007 (0.005–0.009) 0.002 (0.001–0.005) 0.001
Genus Oscillospira 0.011 (0.008–0.015) 0.006 (0.004–0.008) 0.003
Family Enterobacteriaceae, genus undefined 0.076 (0.034–0.189) 0.022 (0.012–0.056) <0.001
Genus Akkermansia 0.006 (0.003–0.016) 0.003 (0.001–0.012) 0.063
The taxa decreased in encephalitis patients
Phylum Bacteroidetes 0.442 (0.221–0.541) 0.510 (0.388–0.644) 0.078
Class Clostridia 0.236 (0.145–0.372) 0.315 (0.221–0.452) 0.075
Class Betaproteobacteria 0.012 (0.007–0.017) 0.022 (0.013–0.031) 0.011
Order Clostridiales 0.236 (0.145–0.372) 0.315 (0.221–0.452) 0.075
Order Burkholderiales 0.012 (0.007–0.017) 0.022 (0.013–0.031) 0.011
Family Lachnospiraceae 0.037 (0.022–0.059) 0.068 (0.056–0.111) <0.001
Genus Prevotella 0.007 (0.003–0.014) 0.025 (0.016–0.106) <0.001
Family Lachnospiraceae, genus undefined 0.022 (0.013–0.035) 0.035 (0.023–0.045) 0.010
Genus Faecalibacterium 0.008 (0.004–0.028) 0.040 (0.022–0.069) 0.001
Genus Ruminococcus 0.004 (0.002–0.009) 0.009 (0.004–0.016) 0.030
Genus Sutterella 0.011 (0.006–0.016) 0.021 (0.012–0.030) 0.005

M, median; IQR, interquartile range.