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. 2020 Aug 25;13:8581–8591. doi: 10.2147/OTT.S257661

Table 2.

Detected Genes

Pathway Genes
Methylation DNMT3A, TET2, IDH1, IDH2, TPMT, MLL, EZH2, SETD2, NPM1
Tumor suppressor WT1, TP53, MPL, APC, CBLB, CBLC, MDM2, CDKN2A
Transcription factor CEBPA, AML1, RUNX1, GATA1, GATA2, GATA3, ETV6, IKZF1, CREBBP, CUX1, ERG, MEF2B, RB1, STAT5B, STAT5A, TCF3, GFI1
Spliceosome and RNA metabolism SF3B1, SRSF2, U2AF1, ZRSR2, PRPF8, DDX41
Chromatin modifiers ASXL1, KDM6A, BCORL1, BCOR, KMT2C, ID3, SETBP1, PHF6, EP300, BLM
Activated Signaling CBL,NRAS,KRAS,HRAS,PTPN11,KIT,CSF1R,CSF3R,JAK1,JAK2,JAK3,SH2B3,NTRK1,NTRK2,ABL,CRLF2,AKT2,AKT3,AMER1,ATM,ATRX,BRAF,EGFR,IL7R,MAP2K4,MAP3K7,NOTCH1,NOTCH2,PIK3CA,PTEN,PDGFRA,SMAD4,SYK,TRAF3,NF1,ETNK1,STAT3,MYD88,FLT3-ITD,FLT3
Cell Metabolism GSTP1, NT5C2, NQO1, PIGA, MTHFR, ELA2, CYP2C19, CYP3A4, GSTM1
Adhesion and cohesion complex RAD21, STAG2, SMC1A, SMC3, FAT1
Others ABCB1, ABCC3, BCL2, CACNA1E, CARD11, CCND1, CD79B, CDA, DIS3, ERCC1, CTLA4, FAM46C, FBXW7, GNAS, MLH1, NF2, TERC, XRCC1, CALR, BIRC3, SRP72, HAX1, TERT, DNAH9, DKC1