Figure 1.

Training periodization of the study (ClinicalTrials.gov ID: NCT02715063). HIIT: high-intensity interval training group; RT: resistance training group; CT: combined training (HIIT + RT) group. HR: heart rate; RM: repetition maximum. Bpm: beats per min (heart rate). To RT group, external load was adjusted weekly to maintain the % of the 1RM (from 40% to 80% of 1RM) and total number of repetitions per exercise (12 to 15 repetitions). The intensity of the exercises increased individually and progressively according to the participants’ response on each day of exercise. The caloric cost of exercise session was calculated based on the one metabolic equivalent (MET) criteria, defined as the amount of oxygen consumed while sitting at rest with a value of 3.5 mL O₂ per kg body weight × min. Additionally, assistance was provided to subjects during the exercise to complete the proposed RM.