Table 1.

Hormone concentrations during clamp studies

	Basal Period	Clamp Period 1	Clamp Period 2
Arterial insulin (µU/mL)
CTR	7 ± 2	23 ± 2	24 ± 1
Bromo	10 ± 2	30 ± 3*	27 ± 4
Hepatic sinusoidal insulin (µU/mL)
CTR	16 ± 3	72 ± 5	69 ± 6
Bromo	19 ± 4*	75 ± 6	82 ± 6*
Arterial glucagon (ng/L)
CTR	42 ± 4	44 ± 6	38 ± 3
Bromo	41 ± 5	47 ± 4	41 ± 10
Hepatic sinusoidal glucagon (ng/L)
CTR	50 ± 7	60 ± 4	56 ± 5
Bromo	51 ± 7	57 ± 3	60 ± 6
Arterial c-peptide (ng/mL)
CTR	0.3 ± 0.1	0.0 ± 0.0	0.0 ± 0.0
Bromo	0.2 ± 0.1	0.0 ± 0.0	0.0 ± 0.0

Data are means ± SE for 2 (basal) or 4 (clamp periods 1 and 2) sampling times; controls (CTR) n = 5; group treated with bromocriptine mesylate (Bromo) n = 6. There were no significant differences between groups with 2-way ANOVA (P = 0.1 between groups for hepatic sinusoidal insulin), and there were no significant differences between clamp periods 1 and 2 within either group; t tests were subsequently used to compare the insulin data during each of the 3 time periods.

^*P < 0.05 between groups by t test.