Table 2.

Effect of a maternal diet high in linoleic acid on relative mRNA expression of genes related to fatty acid metabolism and transport in the labyrinth zone of the rat placenta.

	LLA		HLA		p-Values
	Male	Female	Male	Female	Diet	Sex	Interaction
Genes associated with fatty acid metabolism
Fads1	1.04 ± 0.11	1.07 ± 0.19	0.63 ± 0.06	0.83 ± 0.10	p = 0.010	ns	ns
Fads2	1.08 ± 0.18	1.10 ± 0.22	1.08 ± 0.12	1.30 ± 0.11	ns	ns	ns
Faah	1.13 ± 0.20	1.14 ± 0.28	0.60 ± 0.14	0.85 ± 0.19	ns	ns	ns
Dagla	1.22 ± 0.37	1.09 ± 0.22	0.78 ± 0.22	0.75 ± 0.13	ns	ns	ns
Daglb	1.08 ± 0.17	1.06 ± 0.17	0.63 ± 0.15	0.83 ± 0.14	p = 0.04	ns	ns
Napepld	1.08 ± 0.15	1.08 ± 0.21	0.96 ± 0.09	0.98 ± 0.06	ns	ns	ns
Genes associated with fatty acid transport
Fatp1	1.07 ± 0.14	1.06 ± 0.16	0.61 ± 0.13	1.03 ± 0.21	ns	ns	ns
Fatp4	0.86 ± 0.07	1.23 ± 0.42	0.59 ± 0.10	0.67 ± 0.09	p = 0.03	ns	ns
Fabp3	1.02 ± 0.08	1.04 ± 0.13	1.32 ± 0.12	1.11 ± 0.10	ns	ns	ns
Fabp5	1.02 ± 0.09	1.04 ± 0.14	1.16 ± 0.07	1.07 ± 0.09	ns	ns	ns
Got2	1.12 ± 0.21	1.14 ± 0.24	0.96 ± 0.19	0.95 ± 0.14	ns	ns	ns
Cd36	1.05 ± 0.13	0.85 ± 0.05	0.86 ± 0.05	0.90 ± 0.07	ns	ns	ns
Lpl	1.06 ± 0.13	1.04 ± 0.15	0.85 ± 0.06	0.97 ± 0.06	ns	ns	ns

LLA: low linoleic acid; HLA: high linoleic acid; FADS1: fatty acid desaturase 1 (also known as delta-5 desaturase); FADS2: fatty acid desaturase 2 (also known as delta-6-desaturase FAAH: fatty acid amide hydrolase; DAGLA: diacylglycerol lipase alpha; DAGLB: diacylglycerol lipase beta; NAPEPLD: N-acyl phosphatidylethanolamine phospholipase D. FATP: fatty acid transport protein; FABP: fatty acid binding protein; GOT2: glutamic-oxaloacetic transaminase 2; CD36: cluster of differentiation 36 (also known as fatty acid translocase); LPL: lipoprotein lipase. Placentae from one male and one female per litter were analyzed Data expressed as mean ± SEM and analyzed by two-way ANOVA with diet and sex as two factors. n = 5–8.