Figure 1.

Optimal microbiome composition as a token of human wellbeing. Microbiome composition and structure is one of the factors determining proper human development and health. The roof that represents microbiome may be impermeable and reliable, only provided structures below are solid. A suitable diet and physical activity form the basis for the construction. Metaphorical foundation, which is represented by diet and exercise, underlines principal role of healthy lifestyle in sustaining human health and wellbeing. It is a lifestyle modification one should implement first when commencing the process of building human welfare. The connectors (pillars) between “roof” and “foundation” that cement the construction are pre-, pro-, and postbiotics. A lot of research is currently focused on determining the ideal proportion and shape of each pillar, so all of the construction’s elements depicted in this figure would be in the state of harmony. It is important to note that the composition of the microbiome is also affected by other factors that are not found in this figure, e.g., route of labor, use of medicines, or having siblings.