Fig. 2.

Anatomic location specific structural analysis of smoke-exposed ferret airways using microcomputed tomography. A: manual bronchial wall thickness (BWT) of air control and smoke-exposed ferrets by anatomic location. B: manual luminal diameter. C: manual ratio of BWT to luminal diameter. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. Each region had 2 measurements per ferret (i.e., left, right) that were averaged to a single point estimate per ferret [n = 23 smoke (S), 19 control (C)]. A single point estimate for each of 3 regions was included for each ferret in the all-region analysis (n = 69 S, 57 C). Inferential comparisons by ANOVA with Tukey’s post hoc test.