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. 2020 Aug 18;12(8):2482. doi: 10.3390/nu12082482

Figure 4.

Figure 4

Results of hematoxylin and eosin-stained tissue (scale bar: 200 µm) and regulation of allergy-mediated mRNA expression levels of cytokines and chemokines expression in skin tissues of HDM/DNCB-induced mice. (A) Comparison of the histopathology of dorsal skin lesions after repeated oral administration of SHE on hematoxylin and eosin- stained tissues, (B) toluidine blue-stained skin, (C) congo-red stained skin, (D) regulation of SHE on atopy early stimulation factors (IL-25, IL-33), (E) regulation of SHE on allergic mediated cytokines (IL-6, IL-10, and IFN-γ), and (F) regulation of SHE on allergic mediated chemokines (RANTES, Eotaxin, and TRAC). Densitometry analysis (G). Experiments were performed in triplicates, to confirm repeatability. a–j Values with different alphabets were significantly different at p < 0.05 (n = 8).