Table 1.
Participant Characteristics | Normal-Weight (n = 25) | Obese (n = 12) | |
---|---|---|---|
Age | y | 25.3 ± 0.6 | 28.3 ± 2.0 |
BMI | kg/m2 | 23.3 ± 0.3 | 32.8 ± 0.7 |
Genotype FMO3 G472A rs 226678 |
GG% | 48 | 58 |
GA% | 36 | 25 | |
AA% | 16 | 17 | |
Serum Blood Chemistry | |||
Glucose | mg/dL | 87 ± 1 | 90 ± 2 |
BUN | mg/dL | 16 ± 1 | 15 ± 1 |
Cr | mg/dL | 1.0 ± 0.0 | 0.9 ± 0.0 |
Total bilirubin | mg/dL | 0.9 ± 0.1 | 0.9 ± 0.3 |
Total protein | g/dL | 7.1 ± 0.1 | 7.3 ± 0.3 |
ALP | IU/L | 68 ± 3 | 74 ± 5 |
AST | IU/L | 21 ± 1 | 23 ± 1 |
ALT | IU/L | 21 ± 1 | 26 ± 2 |
eGFR | mL/min/1.73 m2 | 106 ± 3 | 109 ± 4 |
Blood Cell Counts | |||
RBC | ×106/µL | 5.2 ± 0.1 | 5.4 ± 0.1 |
WBC | ×103/µL | 5.9 ± 0.4 | 6.9 ± 0.4 |
Lymphocytes | ×103/µL | 1.9 ± 0.1 | 2.3 ± 0.2 |
Monocytes | ×103/µL | 0.5 ± 0.0 | 0.6 ± 0.0 |
Neutrophils | ×103/µL | 3.2 ± 0.3 | 3.5 ± 0.3 |
Abbreviations: BMI, body mass index; FMO3, flavin-containing monooxygenase isoform 3; BUN, blood urea nitrogen; Cr, creatinine; ALP, alkaline phosphatase; AST, aspartate aminotransferase; ALT, alanine aminotransferase; eGFR, estimated glomerular filtration rate; RBC, red blood cell; and WBC, white blood cell. Values are mean ± SEM.