Table 3.

Key Clinical Studies Testing Marine Omega-3s in Depression and Borderline Personality Disorder.

Population	Dose of Omega-3	Outcome
Major Depressive Disorder [83]	2 g of EPA/day	Improved insomnia, depressed mood and feelings of guilt and worthlessness when added to antidepressant therapy
Major Depressive Disorder [85]	3.3 g EPA/DHA twice daily	Significantly improved the Hamilton Rating Scale for Depression vs. placebo in just 8 weeks on top of standard antidepressant therapy
Treatment-resistant Depression [86]	Ethyl-EPA given at 1 g/day	Improved anxiety, depression, lassitude, libido, sleep and suicidal ideation
Major Depressive Disorder [88]	1-g EPA/day	Equally effective in controlling depressive symptoms compared to fluoxetine
Borderline personality disorder [84]	1-g EPA/day	Reduced aggression and severity of depressive symptoms