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Intestinal permeability is increased in PsA patients and ameliorates with probiotics intake. (A) Heatmap showing too low (dark blue), normal (light blue) and too high (pink) levels of markers of gut permeability (zonulin and α1-antitrypsin) and intestinal inflammation (calprotectin) in PsA patients; Graphs show (B) fecal concentrations of zonulin (left) and α1-antitrypsin (right); (C) fecal concentrations of calprotectin at baseline (0) and week 12 of treatment with probiotics.
