Figure 2.

Effects of HFS diets on serum lipids and glucose homeostasis in the female mice. Serum free fatty acids (A) and triglycerides (B) were not affected by the HFS diets although total (C) and low-density lipoprotein (LDL) (E), but not high-density lipoprotein (HDL) (D) cholesterol were increased with the HFS diets. Fasting glucose (F), but not insulin (G) was increased by the HFS diet. Glucose levels were unchanged from the low-fat-diet (LFD) group with botanical supplementation (F), but glucose tolerance (I) and insulin sensitivity (J) was impaired in all HFS-fed groups. Statistical significance (H) for each panel was set at p < 0.05, (n = 10 per group), variability is expressed as mean ± SD.