Table 2.
P. falciparum and P. vivax positivity in community samples from Thailand, Brazil and PNG, determined by species-specific 18S rRNA (qPCR) versus ultra-sensitive qPCR (us-qPCR)
| P. falciparum positivity (%) | P. vivax positivity (%) | |||||
|---|---|---|---|---|---|---|
| qPCR (95% CI) (n/N) |
us-qPCR (95% CI) (n/N) |
p-valuea | qPCR (95% CI) (n/N) |
us-qPCR (95% CI) (n/N) |
p-valuea | |
| Thailand |
1.3% (0.7–2.5) (10/773) |
1.9% (1.1–3.3) (15/773) |
0.074 |
3.90% (2.7–5.6) (30/773) |
5.00% (3.7–6.9) (39/773) |
0.008 |
| Brazil |
0.80% (0.3–1.9) (5/651) |
1.70% (0.9–3.1) (11/651) (11/651) |
0.041 |
4.90% (3.4–6.9) (32/651) |
6.50% (4.7–8.7) (42/651) |
0.004 |
| PNG |
8.60% (6.8–10.7) (71/828) |
12.20% (10.1–14.7) (101/828) |
< 0.001 |
8.00% (6.3–10.1) (66/828) |
11.50% (9.4–13.8) (95/828) |
< 0.001 |
aMcNemar’s Chi2-test used to determine if gain of infections by us-qPCR was significant