Table 1. Observed Values of Responses for 12 Formulations of Pomegranate Extract Solid Lipid Nanoparticles.
| observed
responses (Y1–Y5) |
|||||
|---|---|---|---|---|---|
| formulation code | particle sizea (nm) | PDIa | zeta potentiala (mV) | entrapment efficiencya (%) | cumulative releasea (%) |
| F1 | 529.5 ± 8.1 | 0.49 ± 0.067 | –22.6 ± 2.4 | 25.15 ± 1.2 | 78.01 ± 1.8 |
| F2 | 611.7 ± 5.6 | 0.33 ± 0.080 | –38.5 ± 2.9 | 55.60 ± 3.6 | 82.60 ± 2.1 |
| F3 | 1823.0 ± 10.2 | 0.59 ± 0.012 | –23.1 ± 1.8 | 61.11 ± 4.2 | 69.98 ± 1.5 |
| F4 | 563.3 ± 9.5 | 0.35 ± 0.050 | –21.6 ± 3.6 | 61.41 ± 3.9 | 88.30 ± 2.3 |
| F5 | 599.4 ± 8.7 | 0.11 ± 0.011 | –22.7 ± 4.7 | 15.37 ± 1.8 | 94.57 ± 3.3 |
| F6 | 938.4 ± 7.5 | 0.80 ± 0.007 | –35.7 ± 3.5 | 63.74 ± 4.4 | 87.85 ± 2.9 |
| F7 | 752.6 ± 13.4 | 1.00 ± 0.002 | –25.6 ± 2.1 | 49.50 ± 2.9 | 81.80 ± 1.6 |
| F8 | 321.9 ± 6.4 | 0.41 ± 0.020 | –30.7 ± 3.1 | 29.50 ± 1.4 | 75.10 ± 2.5 |
| F9 | 362.7 ± 5.9 | 0.42 ± 0.049 | –26.3 ± 2.3 | 31.50 ± 1.8 | 71.47 ± 1.7 |
| F10 | 965.4 ± 8.2 | 0.54 ± 0.038 | –29.2 ± 3.2 | 65.12 ± 4.8 | 75.95 ± 2.6 |
| F11 | 1670.0 ± 9.9 | 1.00 ± 0.001 | –15.6 ± 2.5 | 23.43 ± 1.7 | 87.31 ± 3.1 |
| F12 | 624.3 ± 4.9 | 0.34 ± 0.030 | –28.8 ± 2.4 | 58.71 ± 3.6 | 74.71 ± 2.9 |
a
Results are expressed as the mean of three replicates ± SD.