Table 4. Formulations Composition of Solid Lipid Nanoparticles Loaded with Pomegranate Extract as Suggested by Plackett–Burman Design.
| formulation code | lipid type | lipid (%) | surfactant type | surfactant (%) | co-surfactant (mg) | sonication time (min) | sonication amplitude (%) |
|---|---|---|---|---|---|---|---|
| F1 | precirol | 7 | Tween | 10 | 25 | 10 | 50 |
| F2 | stearic acid | 3 | Tween | 3 | 25 | 10 | 50 |
| F3 | stearic acid | 7 | poloxamer | 10 | 25 | 30 | 100 |
| F4 | stearic acid | 3 | poloxamer | 10 | 150 | 10 | 100 |
| F5 | precirol | 3 | poloxamer | 3 | 25 | 10 | 100 |
| F6 | stearic acid | 7 | Tween | 3 | 25 | 30 | 100 |
| F7 | precirol | 7 | poloxamer | 3 | 150 | 30 | 50 |
| F8 | precirol | 3 | Tween | 3 | 150 | 30 | 100 |
| F9 | precirol | 7 | Tween | 10 | 150 | 10 | 100 |
| F10 | stearic acid | 7 | poloxamer | 3 | 150 | 10 | 50 |
| F11 | precirol | 3 | poloxamer | 10 | 25 | 30 | 50 |
| F12 | stearic acid | 3 | Tween | 10 | 150 | 30 | 50 |