Figure 4.

Effects of miR-203 on keratinocytes HaCaT cells were treated with IL-22 to generate a psoriasis-like dermatitis model in vitro, transfected with anti-miR-203 (anti-NC was used as a negative control), and examined for (a) cell viability using the MTT assay; (b) DNA synthesis capacity by the EdU assay; (c) the mRNA expression of KRT5, KRT10, KRT1, and KRT14 using real-time PCR; and (d) the protein levels of LXR-α, PPAR-γ, ki67, KRT1, KRT10, KRT5, and KRT14 using immunoblotting. *P < 0.05, **P < 0.01.