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. 2020 May 18;19(13):1654–1664. doi: 10.1080/15384101.2020.1762314

Figure 6.

Figure 6.

Cartoon depicting the possible molecular mechanism of cyclin A2 function in the gonocyte-SSC transition. In this model, cyclin A2 directly regulates Akt activation in a phosphorylation–dependent manner and activated Akt regulates the localization of Foxo1 through phosphorylation.