miR-219a inhibits the activation of the TLR4/MYD88 pathway by targeting AIM2. a, AIM2 mRNA, and miR-219a combination determined by dual-luciferase assays. b, AIM2 mRNA expression determined by RT-qPCR. c, AIM2 protein expression determined by western blot. d, TLR4 and MYD88 protein expression in mice determined by western blot. Each group includes 8 mice and each spot represents for a single mouse. Unpaired t test was used to determine statistical significance, *p< 0.05.