Table III.
Top 3 pathways and gene lists of enriched GO categories and KEGG pathways of 30 downregulated genes.
| A, Biological process | ||||
|---|---|---|---|---|
| Pathways | GO term | Gene count | Gene lists | P-value |
| Cell cycle | GO:0007049 | 14 | HMMR, UBE2C, CDCA2, MELK, CCNB2, TYMS, CDK1, MND1, CDCA3, BIRC5, ASPM, CDCA5, TPX2, CDC45 | 2.14467E-05 |
| Mitotic cell cycle phase transition | GO:0044772 | 9 | HMMR, UBE2C, MELK, CCNB2, TYMS, CDK1, CDCA5, TPX2, CDC45 | 6.1294E-05 |
| Cell division | GO:0051301 | 9 | UBE2C, CDCA2, CCNB2, CDK1, CDCA3, BIRC5, ASPM, CDCA5, TPX2 | 8.68163E-05 |
| B, Molecular function | ||||
| Pathways | GO term | Gene count | Gene lists | P-value |
| No statistically significant results | ||||
| C, Cellular component | ||||
| Pathways | GO term | Gene count | Gene lists | P-value |
| No statistically significant results | ||||
| D, KEGG pathway | ||||
| Pathways | GO term | Gene count | Gene lists | P-value |
| Cell cycle | KEGG:04110 | 3 | CCNB2, CDK1, CDC45 | 0.04453008 |