Table 4.

Difference in 6-Month Cytokine Level Between WT VDR and Fok-I Variant

Cytokine	Univariate Model				Multivariate Model
	Fok-I	WT	Unadjusted Difference	Unadjusted P	Multivariate Adjusted Δ Fok-I vs. WT	Multivariate Model P
IL-1β	103.4	147.6	−44.2	.011	−49.4	.0091
IL-6	136.4	133.9	2.5	.91	3	.9
TNF-α	99.1	107.3	−8.2	.52	−10	.48
IFN-γ	107.7	83.7	24	.31	30.4	.23
IL-10	45	40.8	4.2	.64	6	.55
IL-12p70	129.21	141.01	−11.8	.59	−7.1	.76
IL-17	106.58	112.6	−6.02	.73	−2.3	.9
IL-23	20.6	23.7	−3.1	.51	−1.9	.71
CCL-20	156.9	167.9	−11	.63	−6.9	.78

Abbreviations: CCL = chemokine ligand; IFN = interferon; IL = interleukin; TNF = tumor necrosis factor; VDR = vitamin D receptor; WT = wild type.