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. 2020 Jul 17;19(16):2063–2073. doi: 10.1080/15384101.2020.1792686

Figure 4.

Figure 4.

Cell cycle analysis in MM cells treated by different concentrations of GANT61. Statistical graph of cell cycle analysis after treated by various concentrations (0, 2.5, 5, 10 μmol/L) of GANT61 at 24 h in RPMI-8226 cells (a). Cell cycle analysis by flow cytometer after treated by various concentrations (0, 2.5, 5, 10 μmol/L) of GANT61 at 24 h in RPMI-8226 cells (b). Expression of Cyclin D after treated by various concentrations (0, 2.5, 5, 10 μmol/L) of GANT61 at 24 h in RPMI-8226 cells (c, d). Statistical graph of cell cycle analysis after treated by various concentrations (0, 2.5, 5, 10 μmol/L) of GANT61 at 24 h in U266 cells (e). Cell cycle analysis by flow cytometer after treated by various concentrations (0, 2.5, 5, 10 μmol/L) of GANT61 at 24 h in U266 cells (f). Expression of Cyclin D after treated by various concentrations (0, 2.5, 5, 10 μmol/L) of GANT61 at 24 h in U266 cells (g, h). Comparison between two groups was determined by t-test. P value < 0.05 was considered significant. **P < 0.01; ***P < 0.001; NS, no significance; MM, multiple myeloma.