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. 2020 Jul 17;19(16):2063–2073. doi: 10.1080/15384101.2020.1792686

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Figure 5. — Cell cycle analysis in MM cells treated by GANT61 with different treatment times. Statistical graph of cell cycle analysis after treated by 10 μmol/L GANT61 with different treatment times (0, 18, 24, 36 h) in RPMI-8226 cells (a). Cell cycle analysis by flow cytometer after treated by 10 μmol/L GANT61 with different treatment times (0, 18, 24, 36 h) in RPMI-8226 cells (b). Expression of Cyclin D after treated by 10 μmol/L GANT61 with different treatment times (0, 18, 24, 36 h) in RPMI-8226 cells (c, d). Statistical graph of cell cycle analysis after treated by 10 μmol/L GANT61 with different treatment times (0, 18, 24, 36 h) in U266 cells (e). Cell cycle analysis by flow cytometer after treated by 10 μmol/L GANT61 with different treatment times (0, 18, 24, 36 h) in U266 cells (f). Expression of Cyclin D after treated by 10 μmol/L GANT61 with different treatment times (0, 18, 24, 36 h) in U266 cells (f, g). Comparison between two groups was determined by t-test. P value < 0.05 was considered significant. **P < 0.01; ***P < 0.001; NS, no significance. MM, multiple myeloma.