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Rb2 improved insulin sensitivity in 3T3-L1 adipocytes. mRNA levels of adiponectin(a), GLUT4 (b) and IRS-1(c) in 3T3-L1 adipocytes. (d) Phosphorylation (p-AKT) and total AKT levels, p-AKT/AKT ratio in 3T3-L1 adipocytes. Data are presented as mean ± SEM. *P < 0.05, **P < 0.01 compared with control group; #P < 0.05, ##P < 0.01 compared with TNF-α group. BAY 11–7082 (BAY) is an NF-κB pathway inhibitor
