FIGURE 1.

Seed‐based resting state functional connectivity MRI (rs‐fcMRI). Coordinates of peak activations reported from positron emission tomography studies (Column 1) were transformed to MNI152 space as 6 mm spherical regions of interest (ROIs) (Column 2). The brain network associated with each lesion was identified using resting state functional connectivity from a large cohort of normal subjects (Column 3). Positive correlations with the ROI seed are shown in hot colors while negative correlations are shown in cool colors. The positive and negative network derived from each coordinate was thresholded and binarized (Column 4) and all networks were overlapped to identify peak sites where networks overlap across rapid eye movement (REM) activation and deactivation coordinates (Column 5)