TABLE 2.

Multivariate Cox regression models for estimating the overall survival

Characteristics	HR	95% CI	P‐value
Overall survival
Multivariate analysis of YAP expression (Figure 1E)
Age	1.025	1.011‐1.040	.000
Pathologic stage
II vs I	2.156	0.778‐5.979	.140
III vs I	3.917	1.440‐10.656	.007
YAP expression (high vs low)	1.940	1.050‐3.583	.034
Multivariate analysis of AXL expression (Figure 1F)
Age	1.025	1.011‐1.039	.000
Pathologic stage
II vs I	2.147	0.774‐5.952	.142
III vs I	3.621	1.331‐9.852	.012
AXL expression (high vs low)	1.571	1.100‐2.244	.013
Multivariate analysis of combined YAP and AXL expression (Figure 1G)
Age	1.025	1.012‐1.040	.000
Pathologic stage
II vs I	2.165	0.781‐6.002	.138
III vs I	3.792	1.393‐10.320	.009
YAP/AXL expression
YAPHi/AXLLo & YAPLo/AXLHi vs YAPLo/ AXLLo	1.923	1.006‐3.676	.048
YAPHi/ AXLHi vs YAPHi/AXLLo & YAPLo/AXLHi	2.013	1.281‐3.163	.002

P‐values in bold print indicate statistical significance.

Abbreviations: CI, confidence interval; HR, hazard ratio.