TABLE 2.
Summary demographic information for cases and controls in the five analysed samples with brain morphometric measures (cortical thickness, surface areas, and volumes)
| Sample | Characteristic | Controls | Cases | |
|---|---|---|---|---|
| Current depression | cMDD‐STR | Size | 30 | 30 |
| Sex (male/female) | 8/22 | 8/22 | ||
| Age (years) | 54.23 (10.98) | 54.07 (10.96) | ||
| QIDS | 3.3 (2.25) | 13.97 (3.59) | ||
| Medicated | 2 | 18 | ||
| cMDD‐UKB | Size | 735 | 735 | |
| Sex (male/female) | 215/520 | 215/520 | ||
| Age (years) | 59.66 (7.21) | 59.66 (7.21) | ||
| Past depression | rMDD‐STR | Size | 148 | 148 |
| Sex (male/female) | 44/104 | 44/104 | ||
| Age (years) | 58.06 (8.02) | 57.16 (8.81) | ||
| QIDS | 3.49 (2.35) | 5.48 (3.91) | ||
| pMDD‐UKB‐CIDI | Size | 1,665 | 1,665 | |
| Sex (male/female) | 544/1,121 | 544/1,121 | ||
| Age (years) | 60.91 (7.18) | 60.90 (7.19) | ||
| pMDD‐UKB‐ICD | Size | 140 | 140 | |
| Sex (male/female) | 49/91 | 49/91 | ||
| Age (years) | 61.59 (7.64) | 61.59 (7.65) |
Note: Standard deviations for age and QIDS are in brackets. In cMDD‐STR sample participants were considered medicated if they had at least one antidepressant prescription.
Abbreviations: cMDD‐STR, current MDD criteria in STRADL cohort; cMDD‐UKB, probable current MDD criteria in UK Biobank cohort; pMDD‐UKB‐CIDI, lifetime MDD criteria based on the online Composite International Diagnostic Interview (CIDI) in UK Biobank cohort; pMDD‐UKB‐ICD, lifetime MDD criteria based on ICD and hospital records in UK Biobank cohort; QIDS, Quick Inventory of Depressive Symptomatology; rMDD‐STR, remitted MDD criteria in STRADL cohort.