TABLE 3.
Summary demographic information for cases and controls in the five analysed samples with white matter integrity measures (FA and MD)
| Sample | Characteristic | Controls | Cases | |
|---|---|---|---|---|
| Current depression | cMDD‐STR | Size | 40 | 40 |
| Sex (male/female) | 10/30 | 10/30 | ||
| Age (years) | 55.03 (9.77) | 54.23 (10.35) | ||
| QIDS | 3.58 (2.54) | 14.13 (3.88) | ||
| Medicated | 2 | 28 | ||
| cMDD‐UKB | Size | 1,435 | 1,435 | |
| Sex (male/female) | 451/984 | 451/984 | ||
| Age (years) | 60.11 (7.16) | 60.11 (7.16) | ||
| Past depression | rMDD‐STR | Size | 202 | 202 |
| Sex (male/female) | 56/146 | 56/146 | ||
| Age (years) | 57.89 (8.84) | 56.97 (9.28) | ||
| QIDS | 3.53 (2.36) | 5.38 (3.68) | ||
| pMDD‐UKB‐CIDI | Size | 3,418 | 3,418 | |
| Sex (male/female) | 1,094/2,324 | 1,094/2,324 | ||
| Age (years) | 61.46 (7.09) | 61.44 (7.11) | ||
| pMDD‐UKB‐ICD | Size | 289 | 289 | |
| Sex (male/female) | 97/192 | 97/192 | ||
| Age (years) | 61.77 (7.70) | 61.76 (7.70) |
Note: Standard deviations for age and QIDS are in brackets. In cMDD‐STR sample participants were considered medicated if they had at least one antidepressant prescription.
Abbreviations: cMDD‐STR, current MDD criteria in STRADL cohort; cMDD‐UKB, probable current MDD criteria in UK Biobank cohort; pMDD‐UKB‐CIDI, lifetime MDD criteria based on the online Composite International Diagnostic Interview (CIDI) in UK Biobank cohort; pMDD‐UKB‐ICD, lifetime MDD criteria based on ICD and hospital records in UK Biobank cohort; QIDS, Quick Inventory of Depressive Symptomatology; rMDD‐STR, remitted MDD criteria in STRADL cohort.