Appendix Table 2.

The adjusted association between exceeding 80 weekly work hours and adverse safety outcomes stratified by cohort.

	Weekly Work Hours 2002–2007			Weekly Work Hours 2014–2017
	≤80	>80	p-value	≤80	>80	p-value
Crashes	Ref	1.24 (1.04–1.49)	0.02	Ref	1.40 (1.09–1.79)	0.001
Crashes leaving work	Ref	non-estimable		Ref	1.30 (0.88–1.94)	0.19
Near-crashes	Ref	1.80 (1.69–1.93)	<0.0001	Ref	1.68 (1.50–1.87)	<0.0001
Occupational Exposures^	Ref	1.22 (1.10–1.35)	0.0002	Ref	1.58 (1.38–1.82)	<0.0001
Percutaneous Injuries^	Ref	1.21 (1.03–1.42)	0.02	Ref	1.59 (1.28–1.96)	<0.0001
Attentional Failures	Ref	1.79 (1.73–1.85)	<0.0001	Ref	1.52 (1.44–1.60)	<0.0001

All models are adjusted for age, gender, BMI, and specialty. P-values are obtained from likelihood ratio tests.

^{^}Also adjusted for hours of patient care in the month.