Appendix Tables 3A and 3B:

The adjusted association between increasing weekly work hours and adverse safety outcomes stratified by cohort.

	Weekly Work Hours
A: 2002–2007	≤60	>60 & ≤70	>70 & ≤80	>80	p-valuve
Crashes	Ref	1.47 (1.12–1.94)	1.42 (1.10–1.84)	1.59 (1.24–2.02)	0.0007
Crashes leaving work	Ref		non-estimable
Near-crashes	Ref	1.39 (1.25–1.53)	1.72 (1.56–1.89)	2.45 (2.23–2.69)	<0.0001
Occupational Exposures	Ref	1.25 (1.06–1.47)	1.75 (1.52–2.01)	1.88 (1.65–2.15)	<0.0001
Percutaneous Injuries	Ref	1.10 (0.85–1.43)	1.45 (1.17–1.80)	1.63 (1.33–2.00)	<0.0001
Attentional Failures	Ref	1.66 (1.56–1.76)	2.12 (2.01–2.24)	2.83 (2.68–2.98)	<0.0001

			Weekly Work Hours
B: 2014–2017	≤60	>60 & ≤70	>70 & ≤80	>80	p-value
Crashes	Ref	1.01 (0.83–1.22)	1.05 (0.86–1.27)	1.42 (1.09–1.85)	0.13
Crashes leaving work	Ref	1.36 (1.00–1.86)	1.37 (1.00–1.89)	1.60 (1.04–2.46)	0.07
Near-crashes	Ref	1.33 (1.22–1.45)	1.52 (1.39–1.65)	2.12 (1.88–2.40)	<0.0001
Occupational Exposures	Ref	1.29 (1.13-1.46)	1.60 (1.41-1.81)	2.23 (1.91-2.61)	<0.0001
Percutaneous Injuries	Ref	1.20 (0.97–1.49)	1.36 (1.11–1.67)	2.05 (1.61–2.61)	<0.0001
Attentional Failures	Ref	1.29 (1.25–1.34)	1.52 (1.47–1.58)	1.94 (1.83–2.05)	<0.0001

All models are adjusted for age, gender, BMI, and specialty. P-values are obtained from likelihood ratio tests