Table 1.

Performance of the uRDT against Q-Plex ELISA and microscopy detection

	HRP2 Q-Plex ELISA reference, % (95% CI)	pLDH Q-Plex ELISA reference, % (95% CI)	Microscopy reference, % (95% CI)
Sensitivity	58% (53–63)	68% (63–74)	78% (71–84)
Specificity	100% (100–100)	84% (80–88)	74% (70–78)
PPV	100% (100–100)	78% (73–83)	51% (45–57)
NPV	53% (48–58)	77% (72–81)	90% (87–93)

Results are given with associated 95% CIs. Whole blood samples were defined as HRP2- and pLDH-positive with concentrations > 2.30 pg/mL and > 47.8 pg/mL, respectively. Microscopy-positive samples were those with any P. falciparum parasites detected per 1000 WBCs

ELISA enzyme-linked immunosorbent assay, LDH lactate dehydrogenase, PPV positive predicted value, NPV negative predicted value