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microPET images of the nude mice bearing HeLa xenografted tumors at different time points post intravenous injection of the 64Cu–NOTA–FA–FI–PEG–PEI–Ac–Mn3O4 NPs (targeted NPs), the 64Cu–NOTA–FA–FI–PEG–PEI–Ac–Mn3O4 NPs with FA blocking, and the 64Cu–NOTA–FI–PEG–PEI–Ac–Mn3O4 NPs (nontargeted NPs). The whole-body coronal (top) and transverse (bottom) microPET images of nude mice bearing HeLa xenografted tumors are shown. Tumors are indicated by arrows.
