Table 1.

Pathology and genetic testing results for tumor samples

	Pathology	Karyotype	Chromosomal Microarray Analysis	Mutations detected by OncoKids DNA Assay	Gene fusions detected by OncoKids RNA assay
Lymph node sample	Lymph node effaced by an infiltrate of leukemic blasts; Immunophenotype (flow cytometry): CD2 partial, cytoplasmic CD3, CD5, CD7 variable, CD8 variable, CD9 partial, CD10 partial, CD13 partial, CD33 partial, CD38, CD56 variable, CD58, CD71 variable, CD123 variable and TdT partial.	46,XY,t(11;14) (p13;q11.2) [7]/46,XY[1]	arr [GRCh37] 1p33(47655598_47783787)x1,4q12 (54309141_55098549) x1,9p24.3p13.3(204737_34431079)hmz,9p21.3p21.3 (21827991_21954953)x0	No clinically significant somatic variants; negative for PDGFRA mutation detected in the bone marrow sample	STIL(1)-TAL1 (2), FIP1L1 (13)-PDGFRA(12)
Bone marrow sample	Sections of bone marrow biopsy show a hypercellular marrow with significantly increast number of lymphoblasts (approximately 50%); Immunophenotype (flow cytometry): CD2 negative, surface and cytoplasmic CD3, CD5, CD7 variable (abnormally dim to moderate), CD8 dim/negative, CD4 negative and partial/dim CD56. The blasts were negative for B cell and myeloid antigens.	46,XY,t(11;14) (p13;q11.2) [3]/46,sl,del(9) (q13q22)[2]/46, XY[15]	ARR[GRCh37] 1 p33(47655598_47783787)x1,4q12 (54280345_55138638)x1, 9p24.3p13.3(192128_34345782) hmz,9 p21.3(21819462_21996603)x0,9q21.11q31.2 (70966261_109046950)x1a	NM_006206 (PDGFRA): c.2522_2527delinsAAG (p.Arg841_lle843delinsLysVal)	STIL(1)-TAL1(2), FIP1L1(13)-PDGFRA(12)

^aSlight difference in the genomic coordinates of the detected copy number segments is due to the use of different array platforms (OncoScan and CytoScanHD) for the two samples.