Table 3.

Multivariable regression of respiratory distress syndrome by timing of antenatal corticosteroid administration

	Respiratory distress syndrome adjusted odds ratio (95% confidence interval)	p-value
Timing of antenatal corticosteroid administration
< 2 days before delivery	2.07 (1.61–2.66)	<0.001
2 to <7 days before delivery	1.0 (referent)	-
7 to <14 days before delivery	1.40 (1.07–1.83)	0.015
≥ 14 days before delivery	2.34 (1.78–3.07)	<0.001
Gestational age at delivery, per completed week	0.68 (0.65–0.71)	<0.001
Black race	0.59 (0.48–0.72)	<0.001
Male	1.35 (1.12–1.63)	<0.01
Preterm prelabor rupture of membranes	0.71 (0.56–0.91)	<0.01
Delivered by cesarean section	1.24 (1.02–1.52)	0.04
Received magnesium sulfate	0.85 (0.71–1.03)	0.09

Other factors considered in initial models but removed due to p>0.20 include nulliparity and maternal smoking during pregnancy.