Table 5.

Multivariable regression of severe childhood morbidity by timing of antenatal corticosteroid administration (note: limited to participants in BEAM study)

	Severe childhood morbidity* adjusted odds ratio (95% confidence interval)	p-value
Timing of antenatal corticosteroid administration
< 2 days before delivery	1.14 (0.70–1.89)	0.595
2 to <7 days before delivery	1.0 (referent)	-
7 to <14 days before delivery	1.10 (0.69–1.77)	0.690
≥ 14 days before delivery	1.74 (1.02–2.95)	0.042
Gestational age at delivery, per completed week	0.62 (0.57–0.67)	<0.001
Male gender	1.74 (1.21–2.52)	0.003

Other factors considered in initial models but removed due to p>0.20 include preterm prelabor rupture of membranes, receipt of magnesium sulfate prior to delivery (for any indication), maternal smoking during pregnancy, nulliparity, black race, and suspected clinical chorioamnionitis.

^*Severe childhood morbidity included death or moderate to severe cerebral palsy at age 2