Extended Data Figure 3.

Functional analysis CiPCs in retinal degeneration mice (rd1). (a-c) Analysis for the scotopic a-wave of ERG after transplantation of CiPCs at day 45 (a), day 59 (b) and day 77 (c). (d) Scatter plot of pupil constriction measurements for CiPC-injected rd1 mice taken three months after transplantation. (e-f) Measurement of visual acuity (e) and contrast sensitivity (f) for CiPC-injected mice that demonstrated improved pupil response after transplantation and control mice. OR, optokinetic response. For the CiPC-injected rd1 experiment, repeated values are plotted (for n = 1 mouse). In (a-e) n denotes biologically independent animals and the experiment in (f) was performed twice.