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. Author manuscript; available in PMC: 2020 Sep 3.
Published in final edited form as: J Neurosurg. 2018 Dec 1;129(6):1397–1406. doi: 10.3171/2017.7.JNS171286

TABLE 3.

Tumor response categorization at time points following SRS

Time Since SRS No Ipilimumab
Concurrent Ipilimumab
Nonconcurrent Ipilimumab
p Value
Resp* Stab Prog Resp* Stab Prog Resp* Stab Prog
 1.5 mos 45 (69%) 12 (18%) 8 (12%) 34 (62%) 14 (25%) 7 (13%) 94 (70%) 28 (21%) 13 (10%) 0.82

 3 mos 30 (73%) 4 (10%) 7 (17%) 42 (89%) 5 (11%) 0 (0%) 54 (63%) 15 (17%) 17 (20%) 0.002

 6 mos 20 (56%) 2 (5%) 14 (39%) 33 (77%) 9 (21%) 1 (2%) 59 (67%) 7 (8%) 22 (25%) <0.001

Prog = progression; resp = response; stab = stable.

Values are shown as the number of lesions (%) unless otherwise indicated.

*

> 30% tumor volume reduction.

Neither > 30% tumor volume reduction nor increase.

> 30% tumor volume increase.