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. 2020 Sep 2;4(9):e20.00002. doi: 10.5435/JAAOSGlobal-D-20-00002

Table 3.

Preferred First-Line Antibiotic Regimens, Based on the Causative Organism

Organism Preferred first-line regimen
Anaerobes Clindamycin 600 mg IV q6h, or Ticarcillin/clavulanate, 3.1 g IV q4h
Enterobacteriaceae, quinolone-sensitive Ciprofloxacin 400 mg IV q8-12h
Enterobacteriaceae, quinolone-resistant Piperacillin/tazobactam, 3.375 g IV q6h, or Ticarcillin Clavulanate, 3.1 g IV q4h
Pseudomonas aeruginosa Cefepime, 2 g IV q8-12h, with ciprofloxacin 400 mg IV q8-12h
S aureus, methicillin-sensitive Cefazolin, 1-1.5 g IV q6h, or Nafcillin or Oxacillin, 1-2 g IV q4h
S aureus, methicillin-resistant Vancomycin 1g IV q12h, or if allergic, Linezolid 600 mg IV q12h
Streptococcus species Penicillin G, 2-4 million units IV q4h

Adapted from Hatzenbuehler et al (2011).21,24,25 Adaptations are themselves works protected by copyright. So in order to publish this adaptation, authorization must be obtained both from the owner of the copyright in the original work and from the owner of copyright in the translation or adaptation.