Table 3.
Preferred First-Line Antibiotic Regimens, Based on the Causative Organism
| Organism | Preferred first-line regimen |
| Anaerobes | Clindamycin 600 mg IV q6h, or Ticarcillin/clavulanate, 3.1 g IV q4h |
| Enterobacteriaceae, quinolone-sensitive | Ciprofloxacin 400 mg IV q8-12h |
| Enterobacteriaceae, quinolone-resistant | Piperacillin/tazobactam, 3.375 g IV q6h, or Ticarcillin Clavulanate, 3.1 g IV q4h |
| Pseudomonas aeruginosa | Cefepime, 2 g IV q8-12h, with ciprofloxacin 400 mg IV q8-12h |
| S aureus, methicillin-sensitive | Cefazolin, 1-1.5 g IV q6h, or Nafcillin or Oxacillin, 1-2 g IV q4h |
| S aureus, methicillin-resistant | Vancomycin 1g IV q12h, or if allergic, Linezolid 600 mg IV q12h |
| Streptococcus species | Penicillin G, 2-4 million units IV q4h |
Adapted from Hatzenbuehler et al (2011).21,24,25 Adaptations are themselves works protected by copyright. So in order to publish this adaptation, authorization must be obtained both from the owner of the copyright in the original work and from the owner of copyright in the translation or adaptation.