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Stereoview of the K330L HDAC6 CD1–SAHA-BPyne complex (PDB entry 6wyp). Polder OMIT maps showing SAHA-BPyne bound to monomer A and Leu330 (each contoured at 2.5σ). Atoms are color-coded as follows: C, light blue (monomer A), light gray (symmetry mate) or wheat (inhibitor); N, blue; O, red; Zn2+, gray sphere; solvent, small red spheres. Metal-coordination and hydrogen-bond interactions are indicated by solid and dashed black lines, respectively.
