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. 2020 Jul 28;27(1):1115–1124. doi: 10.1080/10717544.2020.1797241

Figure 4.

Figure 4.

Photomicrograph of the corneal tissue of adult male albino rabbits 14 days after carrageenan injection. (A) Group I, non-treated cornea showing increase in epithelial thickness and appearance of horny superficial layer on the corneal surface (arrow), inflammatory cells could be observed in the stroma (arrowhead), as well as newly formed blood vessels (*). (B) Group II (plain drug hydrogel) showing vacuolated epithelial cells (arrow), eosinophilic cytoplasm of others (arrowhead) and stroma showing improved organization of collagen (*). (C) Group III (micellar solution) showing nearly normal epithelial pattern. Stroma showing homogenization of collagen (*). (D) Group IV (TA micelles/chitosan hydrogel) showing nearly normal appearance of the cornea with normal epithelial arrangement and normal stromal pattern. H&E scale bar 50 µm.