Table 5.
Protein target prediction for nitroxoline.
| Target | Common name | Uniprot ID | ChEMBL ID | Target Class | Probability |
|---|---|---|---|---|---|
| Cyclooxygenase-2 | PTGS2 | P35354 | CHEMBL230 | Oxidoreductase | 1 |
| Methionine aminopeptidase 2 | METAP2 | P50579 | CHEMBL3922 | Protease | 1 |
| DNA excision repair protein ERCC-5 | ERCC5 | P28715 | CHEMBL4736 | Other nuclear protein | 0.03123 |
| Ribonuclease H1 | RNASEH1 | O60930 | CHEMBL5893 | Hydrolase | 0.03123 |
| Poly [ADP-ribose] polymerase-1 | PARP1 | P09874 | CHEMBL3105 | Transferase | 0.03123 |
| Proteasome Macropain subunit MB1 | PSMB5 | P28074 | CHEMBL4662 | Protease | 0.03123 |
| Indoleamine 2,3-dioxygenase | IDO1 | P14902 | CHEMBL4685 | Oxidoreductase | 0.03123 |
| Tryptophan 2,3-dioxygenase (by homology) | TDO2 | P48775 | CHEMBL2140 | Oxidoreductase | 0.03123 |